Bio-Enhanced® Na-Rala
R-Lipoic Acid supplements are not all created equal!
If you are considering a Lipoic Acid supplement, don't assume price is the bottom line.
What is Na RALA - Bio-Enhanced® R-Lipoic Acid?
Na RALA is the sodium salt form of R-Lipoic Acid, providing heat stable, low polymer bulk powder and capsules, with fast dissolution rates, high solubility and absorption.
Only R-Lipoic Acid of the highest purity is utilized, after independent HPLC enantioselective analysis confirms the R/S ratio.
Salts of weak acids (R-Lipoic Acid is a weak acid [pKa=4.7]) have a much higher aqueous solubility than the free acid. This being the case, if a material can be taken as a salt (Na RALA) the solubility can be increased and there is improved oral bioavailability.
Bio-Enhanced® Na R-Lipoic Acid is much more stable than R-Lipoic Acid even at elevated temperatures. Heated to over 150° C for 6 hours there is no loss of activity, and polymer formation was undetectable. Pure R-Lipoic Acid would instantaneously polymerize under these conditions.
Bio-Enhanced® Na R-Lipoic Acid requires no refrigeration and does not polymerize, whereas R-Lipoic Acid polymerizes at temperatures slightly above ambient. The polymerization of R-Lipoic Acid is accelerated by light, heat and moisture.
Bio-Enhanced® Na R-Lipoic Acid does not cause heartburn, indigestion or stomach discomfort, unlike unstabilized R-Lipoic Acid.
Why Use Stabilized Bio-Enhanced® Na R-Lipoic Acid?
GeroNova's in-house stability, pharmacokinetic, plasma and tissue studies by PhD chemists using state-of-the-art analytical equipment reveal that commonly used 'raw' (unstabilized) R-Lipoic Acid utilized in most commercially available R-Lipoic Acid products has very low GI absorption and bioavailability, significantly lower than racemic Alpha Lipoic Acid. See our In-House Research Page
Unstabilized R-Lipoic Acid can also contain harmful heavy metals and residual solvents that are very difficult to remove. The processing and stabilization of Bio-Enhanced® Na R-Lipoic Acid removes all traces of residual solvents from the raw material.